32399-12-5

  • 产品名称:2-甲胺基-3-吡啶甲醇
  • 分子式:C7H10N2O
  • 纯度:99%
  • 分子量:138.169
询价

产品详情

 

  • Molecular Formula:C7H10N2O
  • Molecular Weight:138.169
  • Vapor Pressure:0.00023mmHg at 25°C 
  • Refractive Index:1.613 
  • Boiling Point:312.2 °C at 760 mmHg 
  • PKA:13.63±0.10(Predicted) 
  • Flash Point:142.6 °C 
  • PSA:45.15000 
  • Density:1.191 g/cm3 
  • LogP:0.68860 

2-(Methylamino)pyridine-3-methanol(Cas 32399-12-5) Usage

InChI:InChI=1/C7H10N2O/c1-8-7-6(5-10)3-2-4-9-7/h2-4,10H,5H2,1H3,(H,8,9)

32399-12-5 Relevant articles

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Blanch,Fretheim

, p. 1892 (1971)

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A pharmaceutical intermediate 2 - methylamino -3 - pyridine methanol preparation method (by machine translation)

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Paragraph 0067-0074, (2019/10/22)

The invention relates to a shakang [...]...

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

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Page/Page column 100; 101; 102, (2019/07/20)

The present invention provides a compoun...

A preparation method of the midbody shakang zuo

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Paragraph 0039-0046, (2018/05/16)

The invention relates to a preparation m...

RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES

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Page/Page column 69, (2011/12/12)

Provided are 2-pyridone derivatives whic...

32399-12-5 Process route

tert-butyl 2-(methylamino)pyridine-3-carboxylate
338990-70-8

tert-butyl 2-(methylamino)pyridine-3-carboxylate

2-(N-methylamino)-3-hydroxymethylpyridine
32399-12-5

2-(N-methylamino)-3-hydroxymethylpyridine

Conditions
Conditions Yield
With potassium borohydride; zinc(II) chloride; In tetrahydrofuran; toluene; Reagent/catalyst; Solvent; Reflux;
88.2%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;
80%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 3.5h;
76%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
74.6%
2-(methylamino)pyridine-3-carboxylic acid
32399-13-6

2-(methylamino)pyridine-3-carboxylic acid

2-(N-methylamino)-3-hydroxymethylpyridine
32399-12-5

2-(N-methylamino)-3-hydroxymethylpyridine

Conditions
Conditions Yield
With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 20 - 60 ℃; Reagent/catalyst; Temperature; Solvent;
88.1%
With lithium aluminium tetrahydride; In tetrahydrofuran; for 24h; Heating;
 
With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling with ice;
 

32399-12-5 Upstream products

  • 32399-13-6
    32399-13-6

    2-(methylamino)pyridine-3-carboxylic acid

  • 338990-70-8
    338990-70-8

    tert-butyl 2-(methylamino)pyridine-3-carboxylate

  • 49609-84-9
    49609-84-9

    2-Chloronicotinoyl chloride

  • 2942-59-8
    2942-59-8

    2-chloronicotinic acid

32399-12-5 Downstream products

  • 338990-31-1
    338990-31-1

    N-methyl N-(3-[((N-tert-butoxycarbonyl-N-methylamino)acetoxy)methyl]pyridin-2-yl)carbamic acid (1-chloroethyl) ester

  • 338990-63-9
    338990-63-9

    1-[[N-methyl-N-3-[(t-butoxycarbonylmethylamino)acetoxymethyl]pyridin-2-yl]carbamoyloxy]ethyl-1-[(2R,3R)-2-(2,5-difluorophenyl)-2-hydroxy-3-[4-(4-cyanophenyl)thiazol-2-yl]butyl]-1H-[1,2,4]triazol-4-ium chloride

  • 128271-33-0
    128271-33-0

    Methyl-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine

  • 127555-45-7
    127555-45-7

    1-Methyl-3-phenylsulfanyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one