What is the ヒドロキシクロロキン硫酸塩?

ヒドロキシクロロキン硫酸塩 is White cyrstalline solid, while it's Molecular Formula is C 18 H 26 ClN 3 O*H 2 O 4 S. White cyrstalline solid An antimalarial; antirheumatic; lupus erythematosus suppressant

What is the CAS number for ヒドロキシクロロキン硫酸塩?

The CAS number of ヒドロキシクロロキン硫酸塩 is 747-36-4.

What is ヒドロキシクロロキン硫酸塩 (747-36-4) used for?

Hydroxychloroquine is an aminoquinoline with antimalarial, anti-inflammatory, and antiviral activities. It is active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM). Hydroxychloroquine inhibits production of IL-22, IL-17A, and IL-6 induced by phorbol 12-myristate 13-acetate (TPA; ) and ionomycin in peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals or patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). It inhibits accumulation of sequestosome-1 (SQSTM1) puncta, a marker of autophagy, in mouse embryonic fibroblasts (MEFs) in a concentration-dependent manner. Hydroxychloroquine reduces viral titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of infected cynomolgus macaques. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of RA and SLE.InChI:InChI=1/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2/t14-/m0/s1

What is the ヒドロキシクロロキン硫酸塩?

ヒドロキシクロロキン硫酸塩 is White cyrstalline solid, while it's Molecular Formula is C 18 H 26 ClN 3 O*H 2 O 4 S. White cyrstalline solid An antimalarial; antirheumatic; lupus erythematosus suppressant

What is the CAS number for ヒドロキシクロロキン硫酸塩?

The CAS number of ヒドロキシクロロキン硫酸塩 is 747-36-4.

What is ヒドロキシクロロキン硫酸塩 (747-36-4) used for?

Hydroxychloroquine is an aminoquinoline with antimalarial, anti-inflammatory, and antiviral activities. It is active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM). Hydroxychloroquine inhibits production of IL-22, IL-17A, and IL-6 induced by phorbol 12-myristate 13-acetate (TPA; ) and ionomycin in peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals or patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). It inhibits accumulation of sequestosome-1 (SQSTM1) puncta, a marker of autophagy, in mouse embryonic fibroblasts (MEFs) in a concentration-dependent manner. Hydroxychloroquine reduces viral titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of infected cynomolgus macaques. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of RA and SLE.InChI:InChI=1/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2/t14-/m0/s1

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747-36-4

英語名：ヒドロキシクロロキン硫酸塩
化学分子式：C₁₈H₂₆ClN₃O^.H₂SO₄
純度：99%
分子量：433.956

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pd_meltingpoint:240 °C

外観:White cyrstalline solid

ヒドロキシクロロキン硫酸塩は、としても知られています。であるヒドロキシクロロキン硫酸塩はC₁₈H₂₆ClN₃O*H₂O₄Sという記号であらわされますが、これは炭素原子18個、水素原子28個、塩素原子1個、窒素原子3個、酸素原子4個、硫黄原子1個からできています。

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