What is the Гидроксихлорин сульфа?

Гидроксихлорин сульфа is White cyrstalline solid, while it's Molecular Formula is C 18 H 26 ClN 3 O*H 2 O 4 S. White cyrstalline solid An antimalarial; antirheumatic; lupus erythematosus suppressant

What is the CAS number for Гидроксихлорин сульфа?

The CAS number of Гидроксихлорин сульфа is 747-36-4.

What is Гидроксихлорин сульфа (747-36-4) used for?

Hydroxychloroquine is an aminoquinoline with antimalarial, anti-inflammatory, and antiviral activities. It is active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM). Hydroxychloroquine inhibits production of IL-22, IL-17A, and IL-6 induced by phorbol 12-myristate 13-acetate (TPA; ) and ionomycin in peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals or patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). It inhibits accumulation of sequestosome-1 (SQSTM1) puncta, a marker of autophagy, in mouse embryonic fibroblasts (MEFs) in a concentration-dependent manner. Hydroxychloroquine reduces viral titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of infected cynomolgus macaques. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of RA and SLE.InChI:InChI=1/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2/t14-/m0/s1

What is the Гидроксихлорин сульфа?

Гидроксихлорин сульфа is White cyrstalline solid, while it's Molecular Formula is C 18 H 26 ClN 3 O*H 2 O 4 S. White cyrstalline solid An antimalarial; antirheumatic; lupus erythematosus suppressant

What is the CAS number for Гидроксихлорин сульфа?

The CAS number of Гидроксихлорин сульфа is 747-36-4.

What is Гидроксихлорин сульфа (747-36-4) used for?

Hydroxychloroquine is an aminoquinoline with antimalarial, anti-inflammatory, and antiviral activities. It is active against the chloroquine-sensitive NF54 and D6 strains of P. falciparum (IC50s = 16.3 and 15 nM, respectively) but has decreased activity against chloroquine-resistant P. falciparum strains (IC50s = 422.7-1,735.3 nM). Hydroxychloroquine inhibits production of IL-22, IL-17A, and IL-6 induced by phorbol 12-myristate 13-acetate (TPA; ) and ionomycin in peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals or patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). It inhibits accumulation of sequestosome-1 (SQSTM1) puncta, a marker of autophagy, in mouse embryonic fibroblasts (MEFs) in a concentration-dependent manner. Hydroxychloroquine reduces viral titers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the culture supernatant of infected Vero E6 cells but does not reduce SARS-CoV-2 viral titers in an in vitro human airway epithelium model or the respiratory tract of infected cynomolgus macaques. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of RA and SLE.InChI:InChI=1/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/p+2/t14-/m0/s1

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747-36-4

английское имя：Гидроксихлорин сульфа
Брутто-формула：C₁₈H₂₆ClN₃O^.H₂SO₄
Степень чистоты：99%
Молярная масса：433.956

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pd_meltingpoint:240 °C

Внешний вид:White cyrstalline solid

Гидроксихлорин сульфа также известно как . Гидроксихлорин сульфа представлено символом C₁₈H₂₆ClN₃O*H₂O₄S, который состоит из 18 атомов Углерод,28 атомов Водород,1 атома Хлор,3 атомов Азот,4 атомов Кислород и 1 атома Сера..

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