127000-90-2
- 产品名称：1-(((2R,3S)-2-(2,4-二氟苯基)-3-甲基环氧乙基-2-基)甲基)-1H-1,2,4-三唑
- 分子式：C12H11F2N3O
- 纯度：99%
- 分子量：251.236
产品详情
外观:White or off-white Solid
- Molecular Formula:C12H11F2N3O
- Molecular Weight:251.236
- Appearance/Colour:White or off-white Solid
- Boiling Point:371.6±52.0 °C(Predicted)
- PKA:2.75±0.10(Predicted)
- PSA：43.24000
- Density:1.41±0.1 g/cm3 (20 oC 760 Torr)
- LogP:1.87050
127000-90-2 Relevant articles
NOVEL METHOD FOR PREPARATION OF EPOXYTRIAZOLE DERIVATIVES
-
Paragraph 0109; 0115-0116; 0126-0127, (2021/04/13)
The present invention relates to novel p...
Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents
Feng, Xiaoming,He, Qianwen,Liu, Xiaohua,Zhang, Dong,Zhang, Fengcai
supporting information, p. 6961 - 6966 (2021/09/11)
An enantioselective epoxidation of α-sub...
PROCESS FOR PRODUCING EPOXY ALCOHOL COMPOUND
-
Paragraph 0127, (2020/06/29)
A compound represented by formula (II): ...
Triazole alcohol derivative, and preparation method and application thereof
-
, (2020/05/01)
The invention relates to a triazole alco...
127000-90-2 Process route
-
- 126945-34-4,132507-78-9,135270-06-3,135270-09-6,135270-12-1,133775-26-5
(2R,3R)-2-(2,4-difluorophenyl)-3-methanesulfonyloxy-1-(1H-1,2,4-triazol-1-yl)-2-butanol
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- 124627-86-7,132563-70-3,132563-77-0,135270-07-4,135270-10-9,135270-13-2,141611-70-3,127000-90-2
1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)-methyl)-1H-1,2,4-triazole
| Conditions | Yield |
|---|---|
|
With sodium methylate; In methanol; at 0 ℃; for 0.5h;
|
81% |
|
With sodium methylate; In methanol; at 0 - 20 ℃; for 0.5h;
|
72.2% |
|
With sodium methylate; In methanol; at 23 - 28 ℃; for 2h;
|
60% |
|
With sodium methylate; In methanol; at 0 ℃; for 0.25h; Yield given;
|
|
|
With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; Yield given;
|
|
|
With sodium methylate; In methanol; at 0 ℃;
|
-
-
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butane-2-yl dimethyl phosphate
-
- 124627-86-7,132563-70-3,132563-77-0,135270-07-4,135270-10-9,135270-13-2,141611-70-3,127000-90-2
1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)-methyl)-1H-1,2,4-triazole
| Conditions | Yield |
|---|---|
|
With sodium methylate; at 23 - 28 ℃; for 2h;
|
90% |
|
With sodium methylate; In methanol; at 23 - 28 ℃; for 2h;
|
90% |
127000-90-2 Upstream products
-
132507-89-2
(2R,3S)-2-(2,4-Difluoro-phenyl)-1-[1,2,4]triazol-1-yl-butane-2,3-diol
-
124-63-0
methanesulfonyl chloride
-
126918-20-5
(2R*,3R*)-2-(2,4-Difluorophenyl)-1,2,3-butanetriol
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132563-81-6
1-(2,4-difluorophenyl)-2-(tetrahydropyranyloxy)propan-1-one
127000-90-2 Downstream products
-
132507-77-8
Trifluoro-acetic acid (1R,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl ester
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