69559-11-1

  • Product Name:5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentylamine
  • Structural Formula:
  • Purity:99%
  • Molecular Weight:
Inquiry

Product Details

Hot Sale Pharmaceutical Grade 5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentylamine 69559-11-1 supplier

  • Molecular Formula:C9H22N2O
  • Molecular Weight:174.286
  • Vapor Pressure:0.00143mmHg at 25°C 
  • Refractive Index:1.470-1474 
  • Boiling Point:263.6 °C at 760 mmHg 
  • PKA:14.76±0.10(Predicted) 
  • Flash Point:113.2 °C 
  • PSA:49.49000 
  • Density:0.937 g/cm3 
  • LogP:1.12830 

5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentylamine (Cas 69559-11-1) Usage

Uses

5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentylamine is a colorless and pure liquid that can be used as a pharmaceutical intermediate.

InChI:InChI=1/C9H22N2O/c1-3-11(7-8-12)6-4-5-9(2)10/h9,12H,3-8,10H2,1-2H3

69559-11-1 Relevant articles

Method for continuously producing 5-(N-ethyl-N-2-hydroxyethyl amine)-2-pentylamine

-

Paragraph 0045-0058, (2020/08/09)

The invention discloses a method for con...

Application of chiral chloroquine, hydroxychloroquine or salt of the chiral chloroquine and hydroxychloroquine as anti-coronavirus drug target 3CL hydrolase inhibitor for reducing cardiotoxicity

-

Paragraph 0120; 0126-0127, (2020/11/02)

The invention discloses an application o...

HIGH-YIELDING CONTINUOUS FLOW SYNTHESIS OF ANTIMALARIAL DRUG HYDROXYCHLOROQUINE

-

Page/Page column 20-21; 18; 16, (2019/09/12)

Cost effective, semi-continuous flow met...

High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine

Yu, Eric,Mangunuru, Hari P.R.,Telang, Nakul S.,Kong, Caleb J.,Verghese, Jenson,Gilliland, Stanley E.,Ahmad, Saeed,Dominey, Raymond N.,Gupton, B. Frank

, p. 583 - 592 (2018/03/21)

Numerous synthetic methods for the conti...

69559-11-1 Process route

5-(N-ethyl-N-2-hydroxyethylamine)-2-pentanone
74509-79-8

5-(N-ethyl-N-2-hydroxyethylamine)-2-pentanone

rac-5-<N-ethyl-N-(2-hydroxyethyl)amino>-2-pentanamine
69559-11-1

rac-5--2-pentanamine

Conditions
Conditions Yield
With aluminum(III) nitrate nonahydrate; magnesium(II) nitrate hexahydrate; nickel(II) nitrate hexahydrate; yttrium(lll) nitrate hexahydrate; hydrogen; sodium carbonate; sodium hydroxide; In ethanol; ammonia; water; at 80 - 400 ℃; under 4500.45 Torr; Reagent/catalyst; Temperature; Pressure; Solvent; liquid NH3;
95.9%
With methanol; ammonia; und Hydrierung der hergestellten Reaktiongemisches an Raney-Nickel bei 70 at;
 
Multi-step reaction with 2 steps
1: potassium carbonate; hydroxylamine / tetrahydrofuran / 0.17 h / 100 °C / Inert atmosphere; Flow reactor
2: hydrogen / tetrahydrofuran / 4 h / 80 °C / 7500.75 Torr / Inert atmosphere; Flow reactor
With hydrogen; hydroxylamine; potassium carbonate; In tetrahydrofuran;
 
R(-)-5-<N-ethyl-N-(2-hydroxyethyl)amino>-2-pentanamine
159346-86-8

R(-)-5--2-pentanamine

rac-5-<N-ethyl-N-(2-hydroxyethyl)amino>-2-pentanamine
69559-11-1

rac-5--2-pentanamine

Conditions
Conditions Yield
With nickel; In toluene; at 70 ℃; for 12h;
97%

69559-11-1 Upstream products

  • 74509-79-8
    74509-79-8

    5-(N-ethyl-N-2-hydroxyethylamine)-2-pentanone

  • 3695-29-2
    3695-29-2

    5-iodo-2-pentanone

  • 517-23-7
    517-23-7

    3-acetyl-2-oxo-4,5-dihydrofuran

  • 159346-86-8
    159346-86-8

    R(-)-5--2-pentanamine

69559-11-1 Downstream products

  • 137433-23-9
    137433-23-9

    (R)-Hydroxychloroquine

  • 137433-23-9
    137433-23-9

    (S)-Hydroxychloroquine

  • 118-42-3
    118-42-3

    hydroxychloroquine

  • 747-36-4
    747-36-4

    Plaquenil