143655-58-7
- Product Name:N-(3-Fluoro-4-methyl-8-oxo-5,6,7,8-tetrahydro-1-naphthyl)acetamide
 - Structural Formula:
 - Purity:99%
 - Molecular Weight:235.258
 
Product Details
Factory supply commercial supply N-(3-Fluoro-4-methyl-8-oxo-5,6,7,8-tetrahydro-1-naphthyl)acetamide 143655-58-7 Manufacturer
- Molecular Formula:C13H14FNO2
 - Molecular Weight:235.258
 
143655-58-7 Relevant articles
Intermediate for synthesizing camptothecin derivative as well as preparation method and application thereof
-
Paragraph 0109-0110, (2020/08/09)
The invention relates to the technical f...
Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues
Sugimori, Masamichi,Ejima, Akio,Ohsuki, Satoru,Uoto, Kouichi,Mitsui, Ikuo,Kawato, Yasuyoshi,Hirota, Yasuhide,Sato, Keiki,Terasawa, Hirofumi
, p. 2308 - 2318 (2007/10/03)
Nineteen ring A- and F-modified hexacycl...
Aminotetralone derivatives and preparation process thereof
-
, (2008/06/13)
The present invention pertains to a proc...
Hexa-cyclic compound
-
, (2008/06/13)
A novel hexa-cyclic compound, a derivati...
143655-58-7 Process route
- 
                                        
 - 
                                        
                                        
C13H16FNO2
 
                                - 
                                        
                                            
                                         - 
                                        143655-58-7
                                        
8-Acetylamino-6-fluoro-5-methyl-1-tetralone
 
| Conditions | Yield | 
|---|---|
| 
                                        
                                         
                                            
                                                
                                            
                                            With 
                                            
                                            
                                                
                                                    dipotassium peroxodisulfate; 
                                            
                                            
                                                
                                            
                                            In 
                                            
                                                water; acetonitrile; 
                                            
                                            
                                            
                                                
                                                            at 30 ℃;
                                                            
                                                            for 8h;
                                                            
                                            
                                         
                                        
                                     | 
                                    
                                        66% | 
                                
- 
                                        
                                            
                                         - 
                                        143655-57-6
                                        
5-Acetylamino-7-fluoro-8-methyl-1,2,3,4-tetrahydro-naphthalene
 
                                - 
                                        
                                            
                                         - 
                                        143655-58-7
                                        
8-Acetylamino-6-fluoro-5-methyl-1-tetralone
 
| Conditions | Yield | 
|---|---|
| 
                                        
                                         
                                            
                                                
                                            
                                            With 
                                            
                                            
                                                
                                                    potassium permanganate; magnesium sulfate; 
                                            
                                            
                                                
                                            
                                            In 
                                            
                                                acetone; 
                                            
                                            
                                            
                                                
                                                            for 2h;
                                                            
                                                Ambient temperature;
                                                            
                                            
                                         
                                        
                                     | 
                                    
                                        65% | 
                                
143655-58-7 Upstream products
- 
                           
                                143655-57-6
                                5-Acetylamino-7-fluoro-8-methyl-1,2,3,4-tetrahydro-naphthalene
 - 
                           
                                331-43-1
                                4-(4-fluoro-3-methyl-phenyl)-butyric acid
 - 
                           
                                210346-65-9
                                8-amino-6-fluoro-5-methyl-1,2,3,4-tetrahydronaphthalene
 - 
                           
                                143655-54-3
                                methyl 4-(4-fluoro-3-methylphenyl)butanoate
 

                                                        
                                                        
                                                        
                                                        