产品详情
pd_meltingpoint:158-159 °C
- Molecular Formula:C10H8ClNO2S
- Molecular Weight:241.698
- Vapor Pressure:2.19E-05mmHg at 25°C
- Melting Point:158-159 °C
- Refractive Index:1.63
- Boiling Point:371.5 °C at 760 mmHg
- PKA:0.82±0.28(Predicted)
- Flash Point:178.5 °C
- PSA：55.41000
- Density:1.424 g/cm3
- LogP:3.55150
3-Methyl-8-quinolinesulphonyl chloride(Cas 74863-82-4) Usage
|
Chemical Properties |
Off-White to Pale Brown Solid |
|
Uses |
3-Methyl-8-quinolinesulfonyl Chloride (cas# 74863-82-4) is a compound useful in organic synthesis. |
InChI:InChI=1/C10H8ClNO2S/c1-7-5-8-3-2-4-9(15(11,13)14)10(8)12-6-7/h2-6H,1H3
74863-82-4 Relevant articles
Preparation method of 3-methylquinoline-8-sulfonyl chloride
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Paragraph 0046-0049; 0058-0077, (2020/03/17)
The invention belongs to the field of fi...
Aminoguanidines and alkoxyguanidines as protease inhibitors
-
, (2008/06/13)
Aminoguanidine and alkoxyguanidine compo...
HETEROAROMATIC AND THIOHETEROAROMATIC SUBSTITUTED SULFONAMIDE THROMBIN INHIBITORS
-
, (2008/06/13)
Sulfonamide thrombin inhibitors are prov...
74863-82-4 Process route
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- 153886-69-2
3-methyl-8-quinolinesulfonic acid
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- 74863-82-4
8-(chlorosulphonyl)-3-methylquinoline
| Conditions | Yield |
|---|---|
|
With bis(trichloromethyl) carbonate; triethylamine; In toluene; at 25 - 40 ℃; for 3h; Reagent/catalyst; Temperature;
|
178 g |
-
- 612-58-8
3-methylquinoline
-
- 74863-82-4
8-(chlorosulphonyl)-3-methylquinoline
| Conditions | Yield |
|---|---|
|
With chlorosulfonic acid; thionyl chloride; In water;
|
1.58 g (18%) |
74863-82-4 Upstream products
-
612-58-8
3-methylquinoline
-
153886-69-2
3-methyl-8-quinolinesulfonic acid
74863-82-4 Downstream products
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174699-04-8
(2R,4R)-1-[(S)-5-Benzyloxycarbonylamino-2-(3-methyl-quinoline-8-sulfonylamino)-pentanoyl]-4-methyl-piperidine-2-carboxylic acid ethyl ester
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74863-84-6
argatroban
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196936-96-6
[((S)-2-Hydroxy-3-{[(3S,6S,9aS)-6-(3-methyl-quinoline-8-sulfonylamino)-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carbonyl]-amino}-piperidin-1-yl)-imino-methyl]-carbamic acid benzyl ester
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188127-04-0
[Imino-((S)-3-{[(3S,6S,9aS)-6-(3-methyl-quinoline-8-sulfonylamino)-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carbonyl]-amino}-2-oxo-piperidin-1-yl)-methyl]-carbamic acid benzyl ester
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