74892-81-2
- Product Name：(2R,4R)-4-Methylpiperidine-2-carboxylic acid
- Structural Formula：C7H13NO2
- Purity：99%
- Molecular Weight：143.186
Product Details
Factory direct supply commercial supply (2R,4R)-4-Methylpiperidine-2-carboxylic acid 74892-81-2 manufacturer
- Molecular Formula:C7H13NO2
- Molecular Weight:143.186
- Vapor Pressure:0.0024mmHg at 25°C
- Refractive Index:1.464
- Boiling Point:267 °C at 760 mmHg
- PKA:2.48±0.40(Predicted)
- Flash Point:115.3 °C
- PSA：49.33000
- Density:1.062 g/cm3
- LogP:0.78790
(2R,4R)-4-Methylpiperidine-2-carboxylic acid(Cas 74892-81-2) Usage
InChI:InChI=1/C7H13NO2/c1-5-2-3-8-6(4-5)7(9)10/h5-6,8H,2-4H2,1H3,(H,9,10)/t5-,6-/m1/s1
74892-81-2 Relevant articles
A Concise, Enantiospecific Total Synthesis of Chilocorine C Fueled by a Reductive Cyclization/Mannich Reaction Cascade
Lisnyak, Vladislav G.,Snyder, Scott A.
, p. 12027 - 12033 (2020)
Among defensive alkaloids isolated from ...
Preparation method for argatroban intermediate
-
Paragraph 0063; 0064; 0065; 0067, (2018/11/03)
The invention discloses a preparation me...
Enantioselective synthesis of trans-4-methylpipecolic acid
Alegret, Carlos,Santacana, Ferran,Riera, Antoni
, p. 7688 - 7692 (2008/02/13)
(Chemical Equation Presented) An asymmet...
Direct diastereoselective synthesis of (±)-cis- and (±)-trans-4-methylpipecolic acid and derivatives
Cossy, Janine,Belotti, Damien
, p. 2119 - 2120 (2007/10/03)
(±)-cis- or (±)-trans-4-Methylpipecolic ...
74892-81-2 Process route
-
-
(2R,4S)-2-amino-6-methoxy-4-methyl-6-oxohexanoic acid
-
-
74892-81-2
(2R-trans)-4-Methyl-2-piperidinecarboxylic acid
| Conditions | Yield |
|---|---|
|
With
potassium borohydride;
In
water;
at 1 - 60 ℃;
for 3.5h;
|
83.1% |
-
-
C22H25NO2
-
-
74892-81-2
(2R-trans)-4-Methyl-2-piperidinecarboxylic acid
| Conditions | Yield |
|---|---|
|
C22H25NO2;
With
hydrogen; [Rh(NBD)(PPh3)2]PF6;
In
ethanol;
at 50 ℃;
for 4h;
under 760.051 Torr;
With
palladium hydroxide, 20 wt% on carbon; hydrogen;
In
ethanol; water;
at 23 ℃;
for 5h;
under 760.051 Torr;
|
86% |
74892-81-2 Upstream products
-
123811-73-4
4-Methyl-pyridine-2-carboxylic acid; hydrochloride
-
123811-83-6
(+/-)-cis-Boc-4-methylpipecolinic acid
-
1003-67-4
4-methylpyridine-1-oxide
-
1620-76-4
2-Cyano-4-methylpyridin
74892-81-2 Downstream products
-
123811-83-6
(+/-)-cis-Boc-4-methylpipecolinic acid
-
610786-78-2
(2R,4R)-1,4-dimethylpiperidine-2-carboxylic acid
